論文雑誌「ChemMedChem」のカバーアートを制作しました［国立医薬品食品衛生研究所］
弊社で制作しました国立医薬品食品衛生研究所 三澤隆史様のカバーアートが
Wiley社発行の学術雑誌 ChemMedChem
2021年2月号 Front Coverに選ばれました。
Client
国立医薬品食品衛生研究所
有機化学部
三澤 隆史 様
有機化学部
三澤 隆史 様
Journal
ChemMedChem
February 4, 2021 Volume 16, Issue 3 Link
February 4, 2021 Volume 16, Issue 3 Link
Development of Selective TGR5 Ligands Based on the 5,6,7,8‐Tetrahydro‐5,5,8,8‐tetramethylnaphthalene Skeleton
Ryusei Terui, Yuta Yanase, Dr. Hidetomo Yokoo, Prof. Yoshitomo Suhara, Prof. Makoto Makishima, Dr. Yosuke Demizu, Dr. Takashi Misawa
The Front Cover shows that the synthesized compound 4b binds to TGR5, which is a family of rhodopsin‐type GPCRs, and activates its biological functions such as GLP‐1 secretion. 4b can bind to a ligand‐binding domain of TGR5 and strongly activate TGR5 without significant agonistic activity against other nuclear receptors. More information can be found in the
Communication by Yosuke Demizu, Takashi Misawa et al..
Cover design by Art Action Inc. (https://www.artaction.co.jp/).
Ryusei Terui, Yuta Yanase, Dr. Hidetomo Yokoo, Prof. Yoshitomo Suhara, Prof. Makoto Makishima, Dr. Yosuke Demizu, Dr. Takashi Misawa
The Front Cover shows that the synthesized compound 4b binds to TGR5, which is a family of rhodopsin‐type GPCRs, and activates its biological functions such as GLP‐1 secretion. 4b can bind to a ligand‐binding domain of TGR5 and strongly activate TGR5 without significant agonistic activity against other nuclear receptors. More information can be found in the
Communication by Yosuke Demizu, Takashi Misawa et al..
Cover design by Art Action Inc. (https://www.artaction.co.jp/).
