論文雑誌「Inorganic Chemistry」のカバーピクチャーを制作しました［同志社大学］
弊社で制作しました同志社大学 角谷 優樹 様のカバーアートが
アメリカ化学会発行の学術雑誌 Inorganic Chemistry 2021年4月号 Front Coverに選ばれました。
Client
同志社大学
理工学研究科
角谷 優樹 様
理工学研究科
角谷 優樹 様
Journal
Inorganic Chemistry
April 19, 2021, Volume 60, Issue 8 Link
April 19, 2021, Volume 60, Issue 8 Link
Dicopper(II) Complexes of p-Cresol-2,6-Bis(dpa) Amide-Tether Ligands: Large Enhancement of Oxidative DNA Cleavage, Cytotoxicity, and Mechanistic Insight by Intracellular Visualization
Yuki Kadoya, Machi Hata, Yoshiki Tanaka, Atsuhiro Hirohata, Yutaka Hitomi, and Masahito Kodera*
The dicopper(II) complex of the p-cresol-2,6-bis(dpa) amide-tether ligand is 72-fold more active in DNA cleavage with H2O2 and 24-fold more cytotoxic to HeLa cells than related complexes. A Bodipy-modified complex visualizes intracellular behavior. The dicopper complex cleaves DNA and/or RNA of nucleoli and mitochondria to induce selective cell death of cancer cells. See Y. Kadoya, M. Hata, Y. Tanaka, A. Hirohata, Y. Hitomi, and M. Kodera.
Link
Yuki Kadoya, Machi Hata, Yoshiki Tanaka, Atsuhiro Hirohata, Yutaka Hitomi, and Masahito Kodera*
The dicopper(II) complex of the p-cresol-2,6-bis(dpa) amide-tether ligand is 72-fold more active in DNA cleavage with H2O2 and 24-fold more cytotoxic to HeLa cells than related complexes. A Bodipy-modified complex visualizes intracellular behavior. The dicopper complex cleaves DNA and/or RNA of nucleoli and mitochondria to induce selective cell death of cancer cells. See Y. Kadoya, M. Hata, Y. Tanaka, A. Hirohata, Y. Hitomi, and M. Kodera.
Link
